All 3 Uses of

presume
in
The Mill on the Floss

Philip's sense of the situation was too complete for him not to be visited with glancing fears lest he had been intervening too presumptuously in the action of Maggie's conscience, perhaps for a selfish end.†
Chpt 5.3

presumptuously = in a manner that exercises privileges to which one is not entitled

Do you think I'm a presumptuous fool?†
Chpt 5.4 *

presumptuous = exercising privileges to which one is not entitled

But the presumption was, that if it had been good for anything, so successful a man as himself would hardly have been ignorant of it.†
Chpt 3.5 *

Definitions:

(1) (presume as in: presumption of innocence)
to think of something as true or likely, even though it is not known with certainty

Something can be presumed because it seems reasonable or because there is a rule or law demanding such an assumption. For example, in the United States someone charged with a crime is presumed by law to be innocent unless they are proven guilty at a trial.
(2) (presumptuous as in: she is presumptuous)
exercising privileges to which one is not entitled -- such as being too familiar or too bossy