All 3 Uses

i.e.
in
Moby Dick
(Edited)

Long exile from Christendom and civilization inevitably restores a man to that condition in which God placed him, i.e. what is called savagery.
Chpt 55-57 *

i.e. = that is to say or in other words
It is not, perhaps, entirely because the whale is so excessively unctuous that landsmen seem to regard the eating of him with abhorrence; that appears to result, in some way, from the consideration before mentioned: i.e. that a man should eat a newly murdered thing of the sea, and eat it too by its own light.
Chpt 64-66
But even Solomon, he says, "the man that wandereth out of the way of understanding shall remain" (I.E., even while living) "in the congregation of the dead."
Chpt 94-96

Definitions:

(1) (i.e.)
that is to say; or in other words
(2) (meaning too rare to warrant focus)
Much less commonly, i.e. can refer to someone's initials.