All 3 Uses

profane
in
Gone with the Wind
(Auto-generated)

the narrow street was jammed with vehicles—carriages, buggies, ambulances, covered army wagons with profane drivers swearing as the mules struggled through the ruts;†
Chpt 2.8
It was unreal, grotesquely unreal, that morning skies which dawned so tenderly blue could be profaned with cannon smoke that hung over the town like low thunder clouds, that warm noontides filled with the piercing sweetness of massed honeysuckle and climbing roses could be so fearful, as shells screamed into the streets, bursting like the crack of doom, throwing iron splinters hundreds of yards, blowing people and animals to bits.†
Chpt 3.19 *
"Daughter," said Gerald rousing himself, "you are profane.†
Chpt 3.28

Definitions:

(1) (profane as in: don't be profane)
showing no respect for something thought of as sacred
(2) (meaning too rare to warrant focus)
Profane can also mean that something is not sacred or concerned with religion; or that it is not holy because it is unconsecrated, impure or defiled. As a verb it can mean to spoil something considered holy by using it in a degrading or unworthy way.