All 8 Uses of

agony
in
Ulysses, by James Joyce

Martin Cunningham whispered: —I was in mortal agony with you talking of suicide before Bloom.†
Chpt 6

He scratches himself with crossed arms at his ribs, grimacing, and exclaims:) I'm suffering the agony of the damned.†
Chpt 15

THE MOTHER: (In the agony of her deathrattle) Have mercy on Stephen, Lord, for my sake!†
Chpt 15

Inexpressible was my anguish when expiring with love, grief and agony on Mount Calvary.†
Chpt 15

There remained the generic conditions imposed by natural, as distinct from human law, as integral parts of the human whole: the necessity of destruction to procure alimentary sustenance: the painful character of the ultimate functions of separate existence, the agonies of birth and death: the monotonous menstruation of simian and (particularly) human females extending from the age of puberty to the menopause: inevitable accidents at sea, in mines and factories: certain very painful maladies and their resultant surgical operations, innate lunacy and congenital criminality, decimating epidemics: catastrophic cataclysms which make terror the basis of human mentality: seismic upheavals the epice†
Chpt 17

Definition:

intense feelings of suffering -- can be from mental or physical pain