All 3 Uses of

defile
in
Ulysses, by James Joyce

He urged me (stating that he felt it his mission in life to urge me) to defile the marriage bed, to commit adultery at the earliest possible opportunity.†
Chpt 15 *

defile = to spoil the beauty or purity of something

And they shall stone him and defile him, yea, all from Agendath Netaim and from Mizraim, the land of Ham.†
Chpt 15

Many bonafide travellers and ownerless dogs come near him and defile him.†
Chpt 15

Definitions:

(1) (defile as in: it was defiled)
to spoil the beauty or purity of something
in various senses, including:
- pollute a pristine lake
- harm a reputation or good name
- damage or disrespect something sacred
- take a person's virginity in a disrespectful way
(2) (meaning too rare to warrant focus)
meaning too rare to warrant focus:

More rarely (but not uncommon in classic literature), defile can refer to a narrow valley or a march or passage through one.