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however
used in Arrowsmith

2 meanings, 28 uses
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1  —3 uses as in:
However, complications may...
Definition
though (or another expression that connects contrasting ideas)

(Based on idea 1 we might not expect idea 2, but this is a way of saying that even though idea 1 exists, we still have idea 2.  Synonyms include in spite of that, , nevertheless, nonetheless, on the other hand, in contrastand but.)
  • Last night, however, he admitted that you had recently been impertinent to him.
    Chapter 9 (24% in)
Other Uses (with this meaning)
  • However, gentlemen,' I said, 'the impulse that prompts me to consider, in all modesty, your unexpected and probably undeserved honor is the fact that it seems to me that what Congress needs is more forward-looking scientists to plan and more genu-ine trained business men to execute the improvements demanded by our evolving commonwealth, and also the possibility of persuading the Boys there at Washington of the preeminent and crying need of a Secretary of Health who shall completely...
    Chapter 22 (13% in)
  • It was, however, Rippleton Holabird's attitude which most concerned Martin, for Holabird did not let him forget that unless he desired to drift off and be merely a ghostly Rich Woman's husband, he would do well to remember who was Director.
    Chapter 38 (16% in)

There are no more uses of "however" flagged with this meaning in Arrowsmith.

Typical Usage  (best examples)
Dictionary / pronunciation — Google®Dictionary / more samples — Oxford® USDictionary list — Onelook.com®
2  —12 uses as in:
However much she tried...
Definition
to whatever degree (regardless of how much; or whatever unspecified amount)
  • And indeed, as Martin met the staff at lunch, Wickett was the only one whom he did not find courteous, however brief their greetings.
    Chapter 26 (79% in)
however = regardless of how
Other Uses (with this meaning)
  • However much he scoffed, he was gratified when he was treated as a peer by Angus, who spent the summer as extern in the Zenith General Hospital, and who already had the unapproachable dignity of a successful young surgeon.
    Chapter 10 (61% in)
  • however = regardless of how
  • He was cordial now in all his letters, however much he irritated them by the parental advice with which he penalized them for every check he sent.
    Chapter 10 (74% in)
  • however = regardless of how
  • However harshly he may have pointed out Martin's errors, however loftily he may have seemed to ignore his devotion, Gottlieb was as aware of Martin as Martin of him.
    Chapter 12 (39% in)
  • however = regardless of how
  • However harshly he may have pointed out Martin's errors, however loftily he may have seemed to ignore his devotion, Gottlieb was as aware of Martin as Martin of him.
    Chapter 12 (39% in)
  • however = regardless of how
  • He saw that however easily they talked, they were looking at him through the mist of their chatter.
    Chapter 12 (60% in)
  • You knew immediately that he was careful and that he was afraid of nothing, however much he might lack in imagination.
    Chapter 16 (45% in)
  • however = regardless of how
  • He told himself that however much he might relieve the sick, essentially he was a business man, in rivalry with Dr. Winter of Leopolis and Dr. Hesselink of Groningen; that though they might be honest, honesty and healing were less their purpose than making money; that to get rid of avoidable disease and produce a healthy population would be the worst thing in the world for them; and that they must all be replaced by public health officials.
    Chapter 16 (71% in)
  • however = regardless of how
  • When she appeared he explained to her that his discovery was accidental, that most scientific discoveries were accidental, and that no investigator, however great, could do anything more than see the value of his chance results.
    Chapter 24 (14% in)
  • however = regardless of how
  • Gottlieb, Terry Wickett, and Dr. Nicholas Yeo, that long-mustached and rustic biologist whom Martin had first taken for a carpenter, formed an independent faction of their own, and however much he disliked the boisterous Wickett, Martin was dragged into it.
    Chapter 27 (37% in)
  • however = regardless of how
  • ...and however contemptuous he might be, however much he strove for ignoring pride, their nibbling reduced him from arrogant scientist to an insecure, raw-nerved, shrinking old man.
    Chapter 27 (87% in)
  • however = regardless of how
  • ...and however contemptuous he might be, however much he strove for ignoring pride, their nibbling reduced him from arrogant scientist to an insecure, raw-nerved, shrinking old man.
    Chapter 27 (87% in)
however = regardless of how
There are no more uses of "however" flagged with this meaning in Arrowsmith.

Typical Usage  (best examples)
Dictionary / pronunciation — Google®Dictionary / more samples — Oxford® USDictionary list — Onelook.com®
?  —13 uses
exact meaning not specified
  • At first he was annoyed by Sondelius's disturbing presence, however interesting he found his fervors about plague-bearing rats (whom Sondelius hated not at all but whom, with loving zeal, he had slaughtered by the million, with a romantic absorption in traps and poison gas).
    Chapter 30 (94% in)
  • His friend Clif was boorish, his beloved Leora was rustic, however gallant she might be, and he himself wasted energy in hectic busyness and in astonishment at dullness.
    Chapter 8 (19% in)
  • But on night duty, alone, he had to face the self he had been afraid to uncover, and he was homesick for the laboratory, for the thrill of uncharted discoveries, the quest below the surface and beyond the moment, the search for fundamental laws which the scientist (however blasphemously and colloquially he may describe it) exalts above temporary healing as the religious exalts the nature and terrible glory of God above pleasant daily virtues.
    Chapter 11 (58% in)
  • President Truscott said, "Really, I'm too engrossed to consider chimerical schemes, however ingenious they may be.
    Chapter 12 (56% in)
  • However abstracted and impractical, Gottlieb would have made an excellent Sherlock Holmes—if anybody who would have made an excellent Sherlock Holmes would have been willing to be a detective.
    Chapter 13 (37% in)
  • He was not a praise-eater; he was not proud that he should feel misplaced; but however sturdily he struggled he saw himself outside the picture of Wheatsylvania and trudging years of country practice.
    Chapter 17 (39% in)
  • He had never, he raged, however stumbling he might have been, expected to find himself a little pilferer of love, a peeping, creeping area-sneak, and not even successful in his sneaking, less successful than the soda-clerks who swanked nightly with the virgins under the maples.
    Chapter 21 (81% in)
  • However vague the citizens were as to the nature of his wickedness, once they lost faith in him they lost it completely and with joy, and they welcomed an apparently spontaneously generated rumor that he had betrayed his benefactor, their beloved Dr. Pickerbaugh, by seducing Orchid.
    Chapter 24 (54% in)
  • They talked gravely or frivolously of their work, the one sort of work that, since it becomes part of the chain of discovered fact, is eternal, however forgotten the worker's name.
    Chapter 26 (82% in)
  • Thus, however satisfying his work, Martin began to wonder about the perfection of his sanctuary; to wonder why Gottlieb should be so insulting at lunch to neat Dr. Sholtheis, the industrious head of the Department of Epidemiology, and why Dr. Sholtheis should endure the insults; to wonder why Dr. Tubbs, when he wandered into one's laboratory, should gurgle, "The one thing for you to keep in view in all your work is the ideal of co-operation"; to wonder why so ardent a physiologist as...
    Chapter 27 (32% in)
  • He walked out of the McGurk Building in a melancholy, deprecatory way, with one breeches leg bulging over his riding-boots; and however piously he tried, he never remembered to button his blouse over the violet-flowered shirts which, he often confided, you could buy ever so cheap on Eighth Avenue.
    Chapter 27 (75% in)
  • It was still more kind of nice, however agonizing in the taking, to be recognized socially.
    Chapter 29 (58% in)
  • They were affectionate with everybody they met in the corridors, however violent they were in private discussions.
    Chapter 30 (25% in)

There are no more uses of "however" in Arrowsmith.

Typical Usage  (best examples)
Dictionary / pronunciation — Google®Dictionary list — Onelook.com®