All 5 Uses

segregation
in
The Nickel Boys
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Elwood saw it all: Africans persecuted by the white sin of slavery, Negroes humiliated and kept low by segregation, and that luminous image to come, when all those places closed to his race were opened.†
p. 11.9
Dr. King had to tell her in his low, sad rumble about the segregation system that kept colored boys and girls on the other side of the fence.†
p. 12.4
He had relatives who opened businesses downtown and thrived, but a white man savvy to the economics of segregation could turn a real buck.†
p. 20.1 *
They laughed because they knew the drugstore didn't serve colored patrons, and sometimes laughter knocked out a few bricks from the barricade of segregation, so tall and so wide.†
p. 124.8
Despite the segregated campuses, the black boys and white boys passed on news for safety's sake.†
p. 127.6

Definitions:

(1) (segregation)
the act of keeping people or things separate -- especially people due to discrimination based on race, gender, ethnicity, or religion
(2) (meaning too rare to warrant focus)