All 6 Uses

agony
in
I Am Number Four
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I woke screaming in the middle of the night, in agony, terrified as the scar seared itself into my flesh.†
p. 6.9 *

agony = intense suffering
My eyes narrow, my face twists in agony, and—without thinking, without truly knowing what it is that I'm doing—I lunge over Mr. Harris's desk and crash through the plate-glass window, which shatters into a million little pieces behind me.†
p. 340.6
Its body tenses and it writhes in agony.†
p. 393.9
On my stomach, in agony.†
p. 401.4
Bernie Kosar twists his head around and looks at me, his face scrunched tightly in pain and agony and the oncoming death he must feel.†
p. 409.1
The blame for all the pain and agony you've experienced lies with them.†
p. 421.2

Definitions:

(1) (agony)
intense feelings of suffering -- can be from mental or physical pain
(2) (meaning too rare to warrant focus)