All 6 Uses

resignation
in
The God of Small Things
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"I'm afraid I have no option," he said, "but to ask for your resignation."
Chpt 2 *

resignation = to quit a job; or a document expressing that someone is quitting a job
Mother Bear suffered those beatings with mute resignation.
Chpt 8 *

resignation = acceptance of something undesired as unavoidable
Ammu was made to send him back to their father, who had by then resigned his lonely tea-estate job in Assam and moved to Calcutta to work for a company that made carbon black.†
Chpt 1
It was only after Pappachi died that Chacko resigned his job as lecturer at the Madras Christian College, and came to Ayemenem with his Balliol Oar and his Pickle Baron dreams.†
Chpt 2
When Chacko resigned his job in Madras and returned to Ayemenem with a Bharat bottle-sealing machine, it was Velutha who re-assembled it and set it up.†
Chpt 2
Where, with the rush of commerce, despair came home to roost and hardened slowly into resignation.†
Chpt 17

Definitions:

(1) (resignation as in: submitted her resignation)
to quit -- especially a job or position; or a document expressing such an act
(2) (resignation as in: accepted it with resignation)
acceptance of something undesired as unavoidable or the lesser of evils
(3) (meaning too rare to warrant focus)
To resign can also more specifically mean to surrender or give up as in "I was clearly going to lose the chess game, so I resigned;" or "She resigned all pretense."