Both Uses

hamstrung
in
Pretty Little Liars
(Auto-generated)

Shutting the door of the upstairs bathroom, she found the jar of Icy Hot in the closet, pulled down her Nuala Puma warm-up pants, twisted around to see herself in the mirror, and started rubbing the balm all over her back and hamstrings.†
Chpt 19

hamstrings = makes less effective or powerless
Holding her towel in one hand, she reached for the jar, scooped some into her palm, and slid her hand down her pants to rub it into her hamstring.†
Chpt 19 *

hamstring = make less effective or powerless

Definitions:

(1) (hamstrung as in: hamstrung by excessive rules)
make less effective or powerless

Hamstrung originally referred to cutting of tendons or hind legs of cattle or other animals, so that they could not escape.
(2) (meaning too rare to warrant focus)
In addition to using hamstrings in the sense of "making less effective," such as "Their interference hamstrings our progress," in anatomy and sports, hamstrings typically refers to prominent tendons at the back of the knee that attach to the large hamstring muscles which flex the knee. A pulled hamstring is a common athletic injury.