All 3 Uses

resignation
in
Typical American, by Gish Jen
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It was as if, once she'd resigned herself to her new world, something had taken her over — a drive to make it hers.
Chpt 2.11 *

resigned = accepted something undesired as unavoidable or the lesser of evils
Ralph started another list, What It Would Mean If Old Chao Were To Have To Resign In Shame.
Chpt 3.25 *

resign = to quit a job or position
Resignation crossed her face; it was not so much an expression as something that appeared to emanate from her pores.†
Chpt 3.21

Definitions:

(1) (resignation as in: submitted her resignation)
to quit -- especially a job or position; or a document expressing such an act
(2) (resignation as in: accepted it with resignation)
acceptance of something undesired as unavoidable or the lesser of evils
(3) (meaning too rare to warrant focus)
To resign can also more specifically mean to surrender or give up as in "I was clearly going to lose the chess game, so I resigned;" or "She resigned all pretense."