All 5 Uses

profound
in
Typical American, by Gish Jen
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Ralph burst with pride when Grover was paper-trained; and when he'd shrunk the paper down and moved it successfully outside, he felt such a profound sense of accomplishment that all his organs seemed to relax and settle.
Chpt 5.38 *

profound = of greatest intensity or emotional depth
Years later, they would shake their heads and call themselves prejudiced, but at the time they were profoundly disconcerted.†
Chpt 2.10
The problem began to expand to levels at once more profound and absurd.†
Chpt 3.22
His face, which had always appeared smooth, seemed smoother still, in this new state; he almost reminded Helen of a monk a man at some profound leisure.†
Chpt 5.41
Wondering, in the simple way of the profoundly shocked, What happened to the doghouse?†
Chpt 5.45

Definitions:

(1) (profound as in: profound idea)
deep or far-reaching in intellect or consequence
(2) (profound as in: profound sadness)
of greatest intensity or emotional depth
(3) (meaning too rare to warrant focus)