All 6 Uses

opium
in
Ligeia
(Auto-generated)

It was the radiance of an opium-dream—an airy and spirit-lifting vision more wildly divine than the phantasies which hovered vision about the slumbering souls of the daughters of Delos.†
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opium = a powerful narcotic
I had become a bounden slave in the trammels of opium, and my labors and my orders had taken a coloring from my dreams.†
In the excitement of my opium dreams (for I was habitually fettered in the shackles of the drug) I would call aloud upon her name, during the silence of the night, or among the sheltered recesses of the glens by day, as if, through the wild eagerness, the solemn passion, the consuming ardor of my longing for the departed, I could restore her to the pathway she had abandoned—ah, could it be forever?†
But I was wild with the excitement of an immoderate dose of opium, and heeded these things but little, nor spoke of them to Rowena.†
She swallowed the wine unhesitatingly, and I forbore to speak to her of a circumstance which must, after all, I considered, have been but the suggestion of a vivid imagination, rendered morbidly active by the terror of the lady, by the opium, and by the hour.†
—Wild visions, opium-engendered, flitted, shadow-like, before me.†

Definitions:

(1) (opium)
a powerful drug made from a type of poppy; relieves pain and aids sleep, but highly addictive and dangerous when abused recreationally
(2) (meaning too rare to warrant focus)