All 5 Uses

antagonist
in
The Invisible Man, by Wells
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In the morning he had still been simply a legend, a terror; in the afternoon, by virtue chiefly of Kemp's drily worded proclamation, he was presented as a tangible antagonist, to be wounded, captured, or overcome, and the countryside began organising itself with inconceivable rapidity.†
Chpt 26

antagonist = someone who offers opposition or is hostile
Mr. Wicksteed was a man of forty-five or forty-six, steward to Lord Burdock, of inoffensive habits and appearance, the very last person in the world to provoke such a terrible antagonist.†
Chpt 26
He wondered what his antagonist was doing.†
Chpt 27
"Form a line across—" He was hit hard under the ear, and went reeling, trying to face round towards his unseen antagonist.†
Chpt 28
Then came a mighty effort, and the Invisible Man threw off a couple of his antagonists and rose to his knees.†
Chpt 28 *

antagonists = people who offer opposition or are hostile

Definitions:

(1) (antagonist as in: the antagonist in the film)
someone who offers opposition or is hostile
(2) (meaning too rare to warrant focus)
Specialized Definitions of antagonist:
- literature or storytelling: the most important character who opposes the main character or protagonist
- physiology: a muscle that relaxes when another muscle contracts
- chemistry and biology: a substance that interferes with the effect of another substance