All 4 Uses

The Thames
in
Childhood's End
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There were new bridges over the Thames, but in the old places.†
Chpt 9 *

The Thames = the longest river entirely in England; flows eastward through London to the North Sea
Some humorous civil servant had put the Royal Astrociomical Society on the top floor of the great building, a gesture which the Council members fully appreciated as it gave them a magnificent view across the Thames and over the entire northern part of the city.†
Chpt 9
His thoughts were still in turmoil as he crossed to the embankment wall and let his eye follow the Thames on its unhurried way to the sea.†
Chpt 9
A slow smile spread over Jan's face as he turned away from the Thames, back towards the gleaming white facade of the Science Centre.†
Chpt 9

Definitions:

(1) (The Thames)
the longest river entirely in England; flows eastward through London to the North Sea
(2) (meaning too rare to warrant focus)