All 4 Uses

resignation
in
Washington Square, by Henry James
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He left her resignedly; he had got what he wanted.†
Chpt 9 *
I am perfectly resigned to her thinking me a tyrant for a twelvemonth.†
Chpt 12
"We must study resignation," said Mrs. Penniman, hesitating, but sententious at a venture.†
Chpt 30
Resignation to what?†
Chpt 30

Definitions:

(1) (resignation as in: submitted her resignation)
to quit -- especially a job or position; or a document expressing such an act
(2) (resignation as in: accepted it with resignation)
acceptance of something undesired as unavoidable or the lesser of evils
(3) (meaning too rare to warrant focus)
To resign can also more specifically mean to surrender or give up as in "I was clearly going to lose the chess game, so I resigned;" or "She resigned all pretense."