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- When Rosamond was quiet, and Lydgate had left her, hoping that she might soon sleep under the effect of an anodyne, he went into the drawing-room to fetch a book which he had left there, meaning to spend the evening in his work-room, and he saw on the table Dorothea's letter addressed to him.Book 8 — Sunset and Sunrise (51% in)
There are no more uses of "anodyne" in Middlemarch.
Typical Usage (best examples)