All 4 Uses

sovereign
in
Moby Dick
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One complained of a bad cold in his head, upon which Jonah mixed him a pitch-like potion of gin and molasses, which he swore was a sovereign cure for all colds and catarrhs whatsoever, never mind of how long standing, or whether caught off the coast of Labrador, or on the weather side of an ice-island.†
Chpt 1-3 *
It will readily be seen that in this case the alleged right of the Duke to the whale was a delegated one from the Sovereign.†
Chpt 88-90
We must needs inquire then on what principle the Sovereign is originally invested with that right.†
Chpt 88-90
They asked him, then, whether to live or die was a matter of his own sovereign will and pleasure.†
Chpt 109-111

Definitions:

(1) (sovereign)
a supreme ruler; or describing a political body as self-governing
(2) (meaning too rare to warrant focus)
a British coin used until 1914; an adjective describing something as powerfully effective