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used in The Scarlet Letter

2 uses
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changes — especially unanticipated difficulties
  • So great a vicissitude in his life could not at once be received as real.
    Chapter 20 -- The Minister in a Maze (1% in)
  • For upwards of twenty years before this epoch, the independent position of the Collector had kept the Salem Custom-House out of the whirlpool of political vicissitude, which makes the tenure of office generally so fragile.
    Introductory (22% in)

There are no more uses of "vicissitudes" in The Scarlet Letter.

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