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chromosome
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  • Fraternal twins, male and female, one visibly perfect and the other marked by an extra chromosome in every cell of her body.†   (source)
  • "Wonder what my chromosomes are like," I muttered randomly.†   (source)
  • " In a nod to the female chromosomes, it could also be called "the double X solution.†   (source)
  • The disease they have is in their blood, in the structure of their chromosomes.†   (source)
  • It wasn't just about blood relations or shared chromosomes, but something wider, bigger.†   (source)
  • NICK (With that small smile) Not exactly: chromosomes.†   (source)
  • Even the Institute was helpless in erasing the signature of chromosomes.†   (source)
  • He believed, like Doc Peret, that somewhere inside each man is a biological center for the exercise of courage, a piece of tissue that might be touched and sparked and made to respond, a chemical maybe, or a lone chromosome that when made to fire would produce a blaze of valor that even the biles could not extinguish.†   (source)
  • But Ben had bad eyesight--a chance collision of unlucky chromosomes the night of his conception--and perhaps in fact a general weakness of sense mechanisms, so that his hold on physical reality was tentative.†   (source)
  • Chromosomes mean nothing to us, not really.†   (source)
  • Rearrangement of Chromosome Band nqi3 in HeLa Cells   (source)
  • There are countless people under words like "chromosome rearrangement," or "delayed mutation."   (source)
  • "The Chromosome Number of Man," Cytogenics 42 (January 26, 1956).   (source)
  • Banded Marker Chromosomes as Indicators of Intraspecies Cellular Contamination   (source)
    chromosomes = threadlike structures in the cell nucleus that carry genes in a linear order that determine biological traits
  • Cytological Technique, Preconception, and the Counting of Human Chromosomes   (source)
  • To the untrained eye, it simply creates a beautiful mosaic of colored chromosomes.   (source)
  • Mammalian Chromosomes in Vitro: The Karyotype of Man   (source)
  • Deborah traced her mother's chromosomes in the picture with her finger.   (source)
  • Integration Sites of Human Papillomavirus 18 DNA Sequences on HeLa Cell Chromosomes   (source)
  • But chromosomes clumped together, making it impossible to get an accurate count.   (source)
  • They were told that August had what seemed to be a "previously unknown type of mandibulofacial dysostosis caused by an autosomal recessive mutation in the TCOF1 gene, which is located on chromosome 5, complicated by a hemifacial microsomia characteristic of OAV spectrum."   (source)
    chromosome = a threadlike structure in the cell nucleus that carries genes in a linear order that determines biological traits
  • The man who discovered that fact was Walter Nelson-Rees, a chromosome expert who was director of cell culture at the Naval laboratory.   (source)
  • "Loss of Heterozygosity for Alleles on Chromosome 11 in Cervical Carcinoma," American Journal of Human Genetics 49 (1991).   (source)
  • Research into HPV eventually uncovered how Henrietta's cancer started: HPV inserted its DNA into the long arm of her eleventh chromosome and essentially turned off her p53 tumor suppressor gene.   (source)
  • They also knew that there was a string of DNA at the end of each chromosome called a telomere, which shortened a tiny bit each time a cell divided, like time ticking off a clock.   (source)
  • When we hung up I went to call Christoph Lengauer, the cancer researcher who'd given Deborah the painted chromosome picture, but before I could dig out his number, my phone rang again.   (source)
  • Researchers worldwide would soon begin identifying chromosomal disorders, discovering that patients with Down syndrome had an extra chromosome number 21, patients with Klinefelter syndrome had an extra sex chromosome, and those with Turner syndrome lacked all or part of one.   (source)
  • Human-Mouse Hybrid Cell Lines Containing Partial Complements of Human Chromosomes and Functioning Human Genes   (source)
    chromosomes = threadlike structures in the cell nucleus that carry genes in a linear order that determine biological traits
  • The chromosomes inside the cells swelled and spread out, and for the first time, scientists could see each of them clearly.   (source)
  • This allowed scientists to begin mapping human genes to specific chromosomes by tracking the order in which genetic traits vanished.   (source)
  • Christoph had framed a fourteen-by-twenty-inch print of Henrietta's chromosomes that he'd "painted" using FISH.   (source)
  • Their chromosomes and proteins have been studied with such detail and precision that scientists know their every quirk.   (source)
  • We call those chromosomes—those are the things that were colored bright in that big picture I gave you.   (source)
  • Once scientists knew how many chromosomes people were supposed to have, they could tell when a person had too many or too few, which made it possible to diagnose genetic diseases.   (source)
  • Hsu was the University of Texas geneticist whose earlier work with HeLa and other cells had made it possible to discover the correct number of human chromosomes.   (source)
  • Researchers had long believed that human cells contained forty-eight chromosomes, the threads of DNA inside cells that contain all of our genetic information.   (source)
  • That accidental discovery was the first of several developments that would allow two researchers from Spain and Sweden to discover that normal human cells have forty-six chromosomes.   (source)
  • This explained the mechanics of HeLa's immortality: telomerase constantly rewound the ticking clock at the end of Henrietta's chromosomes so they never grew old and never died.   (source)
  • Soon after Harris's HeLa-chicken study, a pair of researchers at New York University discovered that human-mouse hybrids lost their human chromosomes over time, leaving only the mouse chromosomes.   (source)
  • Outside, Deborah threw open the back of her jeep and rummaged through blankets, clothes, and papers until she turned around holding the photo of Henrietta's chromosomes that Christoph Lengauer had given her.   (source)
  • Scientists in laboratories throughout North America and Europe began fusing cells and using them to map genetic traits to specific chromosomes, creating a precursor to the human genome map we have today.   (source)
  • As a Ph.D. student, he'd used HeLa to help develop something called fluorescence in situ hybridization, otherwise known as FISH, a technique for painting chromosomes with multicolored fluorescent dyes that shine bright under ultraviolet light.   (source)
  • This is a woman she has an extra chromosome for changing the subject.†   (source)
  • He's quite terrifying, with his chromosomes, and all.†   (source)
  • If I knew even the chromosomal count ….†   (source)
  • GEORGE: The chromosomes, Martha …. the genes, or whatever they are.†   (source)
  • Your …. your husband was telling me all about the …. chromosomes.†   (source)
  • MARTHA: I know what chromosomes are, sweetie, I love 'em.†   (source)
  • MARTHA: (To NICK) What's all this about chromosomes?†   (source)
  • HONEY (A little thickly) It's because of your chromosomes, dear.†   (source)
  • No panting megacenter to absorb our woe, to distract us from our unremitting sense of time-- time as the agent of our particular ruin, our chromosome breaks, hysterically multiplying tissue.†   (source)
  • Or was it simply who we were that they attacked, our voices, features, gestures, ways of walking and laughing, our eye color, hair color, skin tone, our chromosomes and cells?†   (source)
  • Researchers worldwide would soon begin identifying chromosomal disorders, discovering that patients with Down syndrome had an extra chromosome number 21, patients with Klinefelter syndrome had an extra sex chromosome, and those with Turner syndrome lacked all or part of one.†   (source)
  • 4141 (June 7, 1974); K. S. Lavappa et al., "Examination of ATCC Stocks for HeLa Marker Chromosomes in Human Cell Lines," Nature 259 (January 22, 1976); W K. Heneen, "HeLa Cells and Their Possible Contamination of Other Cell Lines: Karyotype Studies," Hereditas 82 (1976); W A. Nelson-Rees and R. R. Flandermeyer, "HeLa Cultures Defined," Science 191, no.†   (source)
  • For years it was stated that men had forty-eight chromosomes in their cells; there were pictures to prove it, and any number of careful studies.†   (source)
  • In 1953, a group of American researchers announced to the world that the human chromosome number was forty-six.†   (source)
  • She thought of the prehistoric reptiles that came mutating out of the slime and the insects with chromosome damage poking from the desert near some test site, ants the size of bookmobiles—these were movies for the drive-ins of the fifties, a boy and girl yanking at each other's buckles and snaps while the bomb footage unfurls and the giant leeches and scorpions appear on the horizon, all radioactive and seeking revenge, and the fleeing crowds, of course, because in the end these…†   (source)
  • Did you study chromosomal pairs?†   (source)
  • The Rule of 48 was intended as a humorous reminder to scientists, and referred to the massive literature collected in the late 1940's and the 1950's concerning the human chromosome number.†   (source)
  • About his chromosomes.†   (source)
  • But these researchers also went back to reexamine the old pictures, and the old studies—and found only forty-six chromosomes, not forty-eight.†   (source)
  • NICK: Oh, the chromosome business ….†   (source)
  • NICK: Well, chromosomes are ….†   (source)
  • (To MARTHA, now) It's very simple, Martha, this young man is working on a system whereby chromosomes can be altered …. well, not all by himself—he probably has one or two coconspirators—the genetic makeup of a sperm cell changed, reordered …. to order, actually …. for hair and eye color, stature, potency ….†   (source)
  • She and her husband went to the A.B.C.C. to have their chromosomes checked, and though nothing abnormal was found they decided not to try again to have a child.†   (source)
  • It was the late sixties before analyses indeed showed some chromosome aberrations in Hiroshima and Nagasaki survivors, and it would, of course, take much longer to tell what, if any, effects there would be on their progeny.†   (source)
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