De novo synthesis of complex molecules from simple molecules in biochemistry
Trial de novo, or a new trial in the legal system
De novo bank, a state bank that has been in operation for five years or less
In bioinformatics, de novo is a form of sequencing, as in "de novo peptide sequencing." De novo may also be a term used to define methods for making predictions about biological features using only a computational model without extrinsic comparison to existing data. In this context, it may be sometimes interchangeable with the Latin term ab initio.
De novo mutation, a genetic mutation that neither parent possessed nor transmitted.
In financial terminology, numbers reported by newly founded companies (especially the financial services industry) are qualified as "de novo," to distinguish them from older companies. For example, "growth de novo" means growth of newly started companies.
In the context of marketing and advertising, de novo means "again, but in a different way" and is linked to guerrilla and grass roots marketing campaigns.
You have the right to appeal your decision to the Supreme Court, or the Superior Court for a jury trial de novo if I make an error of law or if you don’t agree with my decision.
Jodi Picoult -- Nineteen Minutes
One luckless wight contrived to upset the gravy; and then gravy had to be got up de novo, with due care and formality, Aunt Chloe watching and stirring with dogged precision, answering shortly, to all suggestions of haste, that she "warn’t a going to have raw gravy on the table, to help nobody’s catchings."
Harriet Beecher Stowe -- Uncle Tom’s Cabin
If this is true, it follows that the individual who in particular situations, usually of distress, wishes to convey information about his difficulties to others, does not have to invent a communicational medium de novo….