If Gondor falls, or the Ring is taken, then the Shire will be no refuge.
There go the last of the wains that bear away to refuge the aged the children, and the women that must go with them.
And that way I would not go though all the hosts of Mordor stood before me, and I were alone and had no other refuge.
It is said that when the Eorlingas came out of the North and passed at length up the Snowbourn, seeking strong places of refuge in time of need, Brego and his son Baldor climbed the Stair of the Hold and so came before the Door.
For it is before the walls of Minas Tirith that the doom of our time will be decided, and if the tide be not stemmed there, then it will flow over all the fair fields of Rohan, and even in this Hold among the hills there shall be no refuge.
There are no more uses of "refuge" in the book.
Show samples from other sources
The park serves as a refuge for wildlife.
She took refuge from the sun under a beautiful oak tree.