He wondered often how he would ever recognize the first chill, flush, twinge, ache, belch, sneeze, stain, lethargy, vocal slip, loss of balance or lapse of memory that would signal the inevitable beginning of the inevitable end.
There are no more uses of "twinge" in the book.
Show samples from other sources
It’s been so long since I’ve hugged her, a twinge of guilt rises up inside me.
Colleen Hoover -- Slammed
She has twelve, and I feel a momentary twinge of jealousy.