Intimidated as he was by Colonel Cathcart, he nevertheless found it easier to brave his displeasure than to decline the thoughtful invitation of his two new friends, whom he had met on one of his hospital visits just a few weeks before and who had worked so effectively to insulate him against the myriad social vicissitudes involved in his official duty to live on closest terms of familiarity with more than nine hundred unfamiliar officers and enlisted men who thought him an odd duck.
There are no more uses of "vicissitudes" in the book.
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the project was subject to the usual vicissitudes of exploratory research
Jack stood there, streaming with sweat, streaked with brown earth, stained by all the vicissitudes of a day’s hunting.