Joust, the vulgar but competent bio-physicist, lacking the affection which kept Martin and Terry from reproaching the old man, told Gottlieb that he was a "rotten Director and ought to quit," and was straightway discharged and replaced by a muffin.
One morning he burst in, whiskers alive, and reproached Martin: "What is this mysterious discovery you’re making, Arrowsmith?
There are no more uses of "reproach" in the book.
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She reproached him for being thoughtless and lazy.
Don’t reproach yourself for things beyond your control.