On being excluded, the old ladies changed their tone, and cried through the keyhole that old Sally was drunk; which, indeed, was not unlikely; since, in addition to a moderate dose of opium prescribed by the apothecary, she was labouring under the effects of a final taste of gin-and-water which had been privily administered, in the openness of their hearts, by the worthy old ladies themselves.
There are no more uses of "opium" in the book.
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Sometimes it looked like a French bordello, or a Victorian opium den, or the inside of a spaceship.
Cassandra Clare -- City of Heavenly Fire
There was relief all around, but soon the thread had been overtaken by a multi-participant debate about the efficacy of that war, U.S. foreign policy in general, whether or not we won in Vietnam or Grenada or even WWI, and the ability of the Afghans to self-govern, and the opium trade financing the insurgents, and the possibility of legalization of any and all illicit drugs in America and Europe.