Fanny estranged from him, silent and reserved, was an unnatural state of things; a state which he must break through, and which he could easily learn to think she was wanting him to break through.
Children of the same family, the same blood, with the same first associations and habits, have some means of enjoyment in their power, which no subsequent connexions can supply; and it must be by a long and unnatural estrangement, by a divorce which no subsequent connexion can justify, if such precious remains of the earliest attachments are ever entirely outlived.
There are no more uses of "estrange" in the book.
Show samples from other sources
He has been estranged from his parents since he told them he is gay.
In her attempt to reach out to moderates, she estranged the most passionate in her own party.