Volumnia, growing with the flight of time pinker as to the red in her face, and yellower as to the white, reads to Sir Leicester in the long evenings and is driven to various artifices to conceal her yawns, of which the chief and most efficacious is the insertion of the pearl necklace between her rosy lips.
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The drug is safe and efficacious.
He would weep for hours together, and I verily believe that to the very end this spoiled child of life thought his weak tears in some way efficacious.