And he, and more Than he, and men,—the earth, the heavens, and all:— That,—were I crown’d the most imperial monarch, Thereof most worthy; were I the fairest youth That ever made eye swerve; had force and knowledge More than was ever man’s,—I would not prize them Without her love: for her employ them all; Commend them, and condemn them to her service, Or to their own perdition.
There are no more uses of "perdition" in the play.
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Paul envisaged the whole of mankind, both Jew and Gentile, as being in this fatal state of perdition and as needing a common savior, who is Jesus.
Dictionary of the History of Ideas -- http://etext.lib.virginia.edu/cgi-local/DHI/dhi.cgi?id=dv1-50(retrieved 05/20/06)
Then I considered the fact that they both simply might be crazy, or outcast like Paolo and Francesca, caught up in some weird, shared perdition.