So very great is the improvement Time has brought about in such habits, that a moderate statement of the quantity of wine and punch which one man would swallow in the course of a night, without any detriment to his reputation as a perfect gentleman, would seem, in these days, a ridiculous exaggeration.
There are no more uses of "detrimental" in the book.
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This may sound like an excuse, and perhaps even a little sad, but it’s hard for others to know how consuming one’s arrival in a new land can be, how it will take up every last resource of spirit, which too often can lead to the detriment of most everything else.
Chang-rae Lee -- A Gesture Life
What’s more, they are detrimental to the revolution, so we must oppose them resolutely."