What lay heaviest on my mind was, the consideration that six days intervened between me and the day of departure; for I could not divest myself of a misgiving that something might happen to London in the meanwhile, and that, when I got there, it would be either greatly deteriorated or clean gone.
There are no more uses of "deteriorate" in the book.
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The situation could quickly deteriorate.
Writing, at its best, is a lonely life. Organizations for writers palliate the writer’s loneliness, but I doubt if they improve his writing. He grows in public stature as he sheds his loneliness and often his work deteriorates.