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Multiple Meanings
hamstrung — as in:  hamstrung by excessive rules

Efforts are hamstrung by out-dated regulations.
make less effective or powerless

In addition to using hamstrings in the sense of "making less effective," such as "Their interference hamstrings our progress," in anatomy and sports, hamstrings typically refers to prominent tendons at the back of the knee that attach to the large hamstring muscles which flex the knee.  A pulled hamstring is a common athletic injury.
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